WASHINGTON - (AP) - The Food and Drug Administration says majorbrands of caffeinated alcoholic drinks should be off store shelvesby mid-December.

The FDA issued warning letters to four companies earlier thismonth, saying their drinks were unsafe. The agency said thecombination of caffeine and alcohol in the drinks can lead to a"wide-awake drunk" and have led to alcohol poisoning, caraccidents and assaults.

The agency said Wednesday that Phusion Projects, maker of FourLoko, and United Brands Co., maker of Joose, are no longer shippingthe products and expect them to be off store shelves by Dec. 13.

Charge Beverages and New Century Brewing said they no longer areproducing their alcoholic energy drinks.

At least four states have banned the beverages.