AAA says nearly 51 million Americans are expected to travel at least 50 miles away from their homes this week.
The Sunday before Thanksgiving is often said to be the worst day to travel for Thanksgiving.
There have already been more than 10,000 flight delays nationally Sunday alone.
The Monday and Tuesday after Thanksgiving are said to be the worst days to travel home.
AAA expects to rescue more than 300,000 drivers, usually for flat tires and battery issues.