Hilary Clinton won the Democratic presidential primaries in Connecticut, Pennsylvania, Delaware and Maryland Tuesday.
Bernie Sanders took the victory in Rhode Island.
With Clinton's four victories, she is now has 88 percent of the delegates she needs to become the first woman nominated for president by a major party. Clinton kept her focus firmly on the general election as she spoke to supporters Tuesday night, urging Sanders' loyal supporters to help her unify the Democratic Party and reaching out to GOP voters who may be unhappy with their party's options.
"If you are a Democrat, an independent or a thoughtful Republican, you know that their approach is not going to build an America where we increase opportunity or decrease inequality," Clinton said of the GOP candidates. She spoke in Philadelphia, where Democrats will gather in July for their nominating convention.
AP wire services contributed to this report.