Opening statements were delivered Tuesday in the retrial of Edward Holley — the Orange County man accused of killing 20-year-old Megan McDonald more than two decades ago.

Holley, now 44, is charged with second-degree murder in the 2003 bludgeoning death of McDonald, a college student whose body was found dumped off a dirt path in the Town of Wallkill. His first trial ended in a mistrial last April after jurors were unable to reach a unanimous verdict.

Jury selection lasted a week, and a new panel was seated earlier Tuesday. McDonald’s family, who attended every day of the first trial, were back in court for opening statements.

Prosecutors began by taking jurors back to the day McDonald went missing, recounting how her friends and family were frantically trying to reach her. They described her as a young woman just starting out in life — 5 feet tall, 108 pounds, newly moved into her first apartment, working at American Café in the Galleria Mall, and attending Orange County Community College. They said she was navigating life after the recent death of her father, had a large group of friends, and had recently started seeing someone new.

On the final day of her life — March 13, 2003 — prosecutors said McDonald went to work, then spent time with a friend watching the show "Friends," and that the two used cocaine together. They said she later left to try and find marijuana around midnight. She was bludgeoned to death hours later.

Prosecutors say Holley owed McDonald money and that she had been repeatedly calling him to get it back. They also suggested that jealousy over her seeing someone new may have been a factor in the killing.

McDonald’s body was discovered a day and a half later by a 16-year-old driving down a dirt road near his family’s farm.

Prosecutors said her face was unrecognizable, and clumps of hair had been torn out - and that the evidence will show she was murdered in her car before her body was dumped.

They told jurors Holley has avoided accountability for more than 20 years — calling him a liar and a manipulator — and claimed he gave misleading statements to investigators in 2003, including lying about the kind of car he was driving after a witness spotted it with McDonald's vehicle near Kensington Manor on the night she was killed. They also said her car was later found just feet from his home in the same complex.

Prosecutors further alleged that Holley claimed to have been home for 24 hours during that time — a timeline they said is contradicted by witnesses who saw him at a mutual friend’s party.

In response, Holley’s defense called the prosecution’s case “story time,” telling jurors that McDonald’s death was tragic but that she had made risky choices in her final hours -- which had nothing to do with Holley. They said that on the night of her death, McDonald had spent time with the sister of another ex-boyfriend, Pauly Simpson — a man they described as a “hard-core drug dealer and thug” with a documented history of domestic violence.

The case has long been surrounded by questions, including why it took more than 20 years to bring it to trial. Investigators failed to test DNA collected in 2003 from a vehicle linked to another former suspect until just last year, shortly after the mistrial. While the results weren’t a match for McDonald, both sides are expected to address the issue again in this retrial.

The Orange County District Attorney’s Office previously said there wasn’t enough evidence to convict Holley — and wasn’t consulted by State Police when they made the arrest in 2023. Due to a conflict, two special prosecutors from outside the county are now handling the case.

Testimony is expected to start this week, and the trial is scheduled to run through mid-March.

Holley remains in jail without bail. If convicted, he faces up to 25 years to life in prison.